Jonathan has been involved in pulmonary research since 2014. He worked in vaccine development for Parainfluenza virus, and he has studied the pathological progression of Acute Respiratory Distress Syndrome, Idiopathic Pulmonary Fibrosis, and Scleroderma. Jonathan joined our lab in 2017 and is currently studying the roles of the PrrF and PrrH small RNAs in the context of Pseudomonas aeruginosa lung infections. His focus is on developing bioinformatic pipelines for discovery of novel iron and heme regulatory factors that are relevant to acute and chronic P. aeruginosa lung infection.
Djapgne L, Panja S, Brewer LK, Gans J, Kane MA, Woodson SA, Oglesby-Sherrouse AG. (2018) The Pseudomonas aeruginosa PrrF1 and PrrF2 small regulatory RNAs (sRNAs) promote 2-alkyl-4-quinolone production through redundant regulation of the antR mRNA. Journal of Bacteriology. In press.
Gans J, Osborne J, Cheng J, Djapgne L, Oglesby-Sherrouse AG. (2018) Sequence-specific affinity chromatography of bacterial small regulatory RNA-binding proteins from bacterial cells. Methods Mol Biol 1737:341-350.
D’Alessio, FR, Craig JM, Singer BS, Files DC, Mock JR, Garibaldi BT, Fallica J, Tripathi A, Mandke P, Gans JH, Limjunyawong N, Sidhaye VK, Heller NM, Mitzner W, King LS, and Aggarwal NR. Enhanced Resolution of Experimental ARDS through IL-4-Mediated Lung Macrophage Reprogramming. American Journal of Physiology – Lung Cellular and Molecular Physiology 2016 Feb 19.
Bain, W, Tripathi A, Mandke P, Gans J, D’Alessio FR, Sidhaye VK, and Aggarwal NR. Low-dose oxygen enhances macrophage-derived bacterial clearance following cigarette smoke exposure. Journal of Immunology Research. 2016 Jun 14.